Siloxane-Silver Nanofluid as Potential Self-Assembling Disinfectant: A Preliminary Study on the Role of Functional Alkoxysilanes

Antimicrobial drug resistance among bacterial and fungal communities have been created a huge challenge for clinicians in treating infections. Conventional antibiotics get non-functional with time due to the rapid adaptation of microorganisms environment. Therefore, exploring alternative antimicrobial drugs/nanomaterials treat such infections is highly needed. an conventional antibiotics, functional alkoxysilane capped Ag-NPs synthesized from 3-aminopropyltrimethoxysilane mediated conversion silver cations presence three different organic reducing agents, i.e., cyclohexanone, 3-glycidoxypropyltrimethoxysilane formaldehyde. The potential nanoparticles was tested against Acinetobacter bauminnii, Candida albicans (mostly causes nosocomial infections) sporangiospores Mucorales (Rhizopus arrhizus), which showed promising result. In addition low MIC values, these shown variable killing dynamics as function agents. Further, functionalized were mixed siloxane polymer prepare siloxane-silver nanofluids. Siloxane-silver nanofluid can be self-assembled when diluted desirable volatile solvent on any inanimate surfaces medical catheters, surgical clothes bandages. Finally, sprays converted into thin films sterile plastic strips examined their antibacterial activity drug-resistant bacteria A baumannii. film has found reagents that control morphology film.